Wade Wilson left his family as a teenager and traveled around the country while getting military training. Later, he had a incurable cancer and hoping to cure his cancer he volunteered for an experiment that's supposed to give you Wolverine's healing factor. It ended up boosting his cancer giving him a disfigured body also becoming severely mentally unbalanced. After trying to be killed, his healing factor kicked in which gave him the advantage. Later he escaped, calling himself Deadpool.